Neurogenesis of Neural Crest-Derived Periodontal Ligament Stem Cells by EGF and bFGF
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چکیده
منابع مشابه
The potential of human-derived periodontal ligament stem cells to osteogenic differentiation: An In vitro investigation
Background: Periodontal ligament stem cells (PDLSCs) are considered as a type of mesenchymal stem cell that is beneficial target for numerous clinical applications in periodontal tissue regeneration therapy. Materials and Methods: This study examined the effects of dexamethasone (Dex) on human PDLSCs in vitro. PDLSCs obtained from the roots of patient’s teeth were cultured with Dex (0....
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Millions of people experience consequential tooth loss related to irretrievable damage of the periodontium caused by deep caries, severe periodontal diseases or irreversible trauma, resulting in a decreased quality of life. Hence, dental scientists have focused much attention on tissue engineering techniques in an effort to address this condition. The periodontium is composed mainly of two soft...
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Objective(s): Adipose-derived stem cells (ADSCs), with suitable and easy access, are multipotential cells that have the ability for differentiation into other mesodermal and transdifferentiate into neural phenotype cells. In this study, Lithium chloride (LiCl) was used for in vitro transdifferentiation of rat ADSCs into neuron-like cells (NLCs).<stro...
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Introduction: Recent reports showed allogenic neurotrophic Schwann-cell factors could induce neural differentiation of mesenchymal stem cells, so we want to investigate whether heterogeneic neurotrophic Schwann-cell factors could induce neural differentiation of periodontal ligament stem cells (PDLSCs). Material and methods: We isolated and multiplied PDLSCs from periodontal ligament of 8 month...
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Hematopoietic stem cells (HSCs) in the endosteum of mesoderm-derived appendicular bones have been extensively studied. Neural crest-derived bones differ from appendicular bones in developmental origin, mode of bone formation and pathological bone resorption. Whether neural crest-derived bones harbor HSCs is elusive. Here, we discovered HSC-like cells in postnatal murine mandible, and benchmarke...
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ژورنال
عنوان ژورنال: Journal of Cellular Physiology
سال: 2013
ISSN: 0021-9541
DOI: 10.1002/jcp.24468